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1

The Molecular and Cellular Basis of Neurodegenerative Diseases || Parkinson’s Disease and Other Synucleinopathies

Cookson, Mark R.

Year:

2018

Language:

english

File:

PDF, 1.35 MB

english, 2018

2

Mapping complex disease traits with global gene expression

Cookson, William, Liang, Liming, Abecasis, Gonçalo, Moffatt, Miriam, Lathrop, Mark

Journal:

Nature Reviews Genetics

Year:

2009

Language:

english

File:

PDF, 433 KB

english, 2009

3

THE BIOCHEMISTRY OF PARKINSON'S DISEASE*

Cookson, Mark R.

Journal:

Annual Review of Biochemistry

Year:

2005

Language:

english

File:

PDF, 362 KB

english, 2005

4

Catalytic Function of PLA2G6 Is Impaired by Mutations Associated with Infantile Neuroaxonal Dystrophy but Not Dystonia-Parkinsonism

Engel, Laura A., Jing, Zheng, O'Brien, Daniel E., Sun, Mengyang, Kotzbauer, Paul T., Cookson, Mark R.

Journal:

Year:

2010

Language:

english

File:

PDF, 340 KB

english, 2010

5

Converging pathways in neurodegeneration, from genetics to mechanisms

Gan, Li, Cookson, Mark R., Petrucelli, Leonard, La Spada, Albert R.

Journal:

Nature Neuroscience

Year:

2018

Language:

english

File:

PDF, 2.15 MB

english, 2018

6

Recession, local employment trends and change in self-reported health of individuals: A longitudinal study in England and Wales during the ‘great recession’

Curtis, Sarah, Norman, Paul, Cookson, Richard, Cherrie, Mark, Pearce, Jamie

Journal:

Year:

2019

Language:

english

File:

PDF, 928 KB

english, 2019

7

The Undiagnosed Disease Burden Associated with Alpha-1 Antitrypsin Deficiency Genotypes

Nakanishi, Tomoko, Forgetta, Vincenzo, Handa, Tomohiro, Hirai, Toyohiro, Mooser, Vincent, Lathrop, Mark G., Cookson, William O.C.M., Richards, J. Brent

Journal:

European Respiratory Journal

Year:

2020

File:

PDF, 7.92 MB

2020

8

Roles of the proteasome in neurodegenerative disease: Refining the hypothesis

Mark R. Cookson

Journal:

Annals of Neurology

Year:

2004

Language:

english

File:

PDF, 57 KB

english, 2004

9

Methods for assessing the cost-effectiveness of public health interventions: Key challenges and recommendations

Helen Weatherly, Michael Drummond, Karl Claxton, Richard Cookson, Brian Ferguson, Christine Godfrey, Nigel Rice, Mark Sculpher, Amanda Sowden

Journal:

Year:

2009

Language:

english

File:

PDF, 205 KB

english, 2009

10

7. Mitochondrial function and morphology are impaired in parkin mutant fibroblasts

Heather Mortiboys, Kelly Jean Thomas, Werner J.H. Koopman, Stefanie Klaffke, Patrick Abou-Sleiman, Mark R Cookson, Oliver Bandmann

Journal:

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

11

Soap is not enough: handwashing practices and knowledge in refugee camps, Maban County, South Sudan

Phillips, Raina M, Vujcic, Jelena, Boscoe, Andrew, Handzel, Thomas, Aninyasi, Mark, Cookson, Susan T, Blanton, Curtis, S Blum, Lauren, Ram, Pavani K

Journal:

Conflict and Health

Year:

2015

Language:

english

File:

PDF, 591 KB

english, 2015

12

The impact of fraudulent and irreproducible data to the translational research crisis - solutions and implementation

Schulz, Jörg B., Cookson, Mark R., Hausmann, Laura

Journal:

Journal of Neurochemistry

Year:

2016

Language:

english

File:

PDF, 400 KB

english, 2016

13

Addressing unmet needs in understanding asthma mechanisms

Edwards, Michael R., Saglani, Sejal, Schwarze, Jurgen, Skevaki, Chrysanthi, Smith, Jaclyn A., Ainsworth, Ben, Almond, Mark, Andreakos, Evangelos, Belvisi, Maria G., Chung, Kian Fan, Cookson, William,

Journal:

European Respiratory Journal

Year:

2017

Language:

english

File:

PDF, 1.56 MB

english, 2017

14

Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies

Erskine, Daniel, Ding, Jinhui, Thomas, Alan J., Kaganovich, Alice, Khundakar, Ahmad A., Hanson, Peter S., Taylor, John-Paul, McKeith, Ian G., Attems, Johannes, Cookson, Mark R., Morris, Christopher M.

Journal:

Movement Disorders

Year:

2018

Language:

english

File:

PDF, 540 KB

english, 2018

15

The role of monogenic genes in idiopathic Parkinson’s disease

Reed, Xylena, Bandrés-Ciga, Sara, Blauwendraat, Cornelis, Cookson, Mark R.

Journal:

Neurobiology of Disease

Year:

2018

Language:

english

File:

PDF, 1.50 MB

english, 2018

16

In Vitro CRISPR/Cas9-Directed Gene Editing to Model LRRK2 G2019S Parkinsonâs Disease in Common Marmosets

Vermilyea, Scott C., Babinski, Alexander, Tran, Nina, To, Samantha, Guthrie, Scott, Kluss, Jillian H., Schmidt, Jenna Kropp, Wiepz, Gregory J., Meyer, Michael G., Murphy, Megan E., Cookson, Mark R., E

Journal:

Scientific Reports

Year:

2020

File:

PDF, 6.47 MB

2020

17

THREE-DIMENSIONAL RECONSTRUCTION OF BENIGN LYMPHOID AGGREGATES IN BONE MARROW TREPHINES

SALISBURY, JONATHAN R., DEVERELL, MARK H., COOKSON, M. JOHN

Journal:

The Journal of Pathology

Year:

1996

Language:

english

File:

PDF, 408 KB

english, 1996

18

THREE-DIMENSIONAL RECONSTRUCTION OF NON-HODGKIN'S LYMPHOMA IN BONE MARROW TREPHINES

SALISBURY, JONATHAN R., DEVERELL, MARK H., SEATON, JANE M., COOKSON, M. JOHN

Journal:

The Journal of Pathology

Year:

1997

Language:

english

File:

PDF, 3.27 MB

english, 1997

19

Genetics of Parkinson's disease and parkinsonism

John Hardy, Huaiban Cai, Mark R. Cookson, Katrina Gwinn-Hardy, Andrew Singleton

Journal:

Annals of Neurology

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

20

Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts

Heather Mortiboys, Kelly Jean Thomas, Werner J. H. Koopman, Stefanie Klaffke, Patrick Abou-Sleiman, Simon Olpin, Nicholas W. Wood, Peter H. G. M. Willems, Jan A. M. Smeitink, Mark R. Cookson, Oliver B

Journal:

Annals of Neurology

Year:

2008

Language:

english

File:

PDF, 517 KB

english, 2008

21

Mechanisms in dominant parkinsonism: The toxic triangle of LRRK2, α-synuclein, and tau

Jean-Marc Taymans, Mark R. Cookson

Journal:

Year:

2010

Language:

english

File:

PDF, 341 KB

english, 2010

22

DJ-1, PINK1, and their effects on mitochondrial pathways

Mark R. Cookson

Journal:

Movement Disorders

Year:

2010

Language:

english

File:

PDF, 67 KB

english, 2010

23

The expression of the glial glutamate transporter protein EAAT2 in motor neuron disease: an immunohistochemical study

Anne E. Fray, Paul G. Ince, Steven J. Banner, Ian D. Milton, Philip A. Usher, Mark R. Cookson, Pamela J. Shaw

Journal:

European Journal of Neuroscience

Year:

1998

Language:

english

File:

PDF, 553 KB

english, 1998

24

Peroxynitrite and Hydrogen Peroxide Induced Cell Death in the NSC34 Neuroblastoma × Spinal Cord Cell Line: Role of Poly(ADP-Ribose) Polymerase

Mark R. Cookson, Paul G. Ince, Pamela J. Shaw

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 1.10 MB

english, 1998

25

Development and Characterisation of a Glutamate-Sensitive Motor Neurone Cell Line

Christopher J. Eggett, Stephen Crosier, Philip Manning, Mark R. Cookson, Fiona M. Menzies, Calum J. McNeil, Pamela J. Shaw

Journal:

Journal of Neurochemistry

Year:

2000

Language:

english

File:

PDF, 264 KB

english, 2000

26

Identification and characterization of the human parkin gene promoter

Andrew West, Matt Farrer, Leonard Petrucelli, Mark Cookson, Paul Lockhart, John Hardy

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 528 KB

english, 2001

27

Selective loss of neurofilament expression in Cu/Zn superoxide dismutase (SOD1) linked amyotrophic lateral sclerosis

Fiona M. Menzies, Andrew J. Grierson, Mark R. Cookson, Paul R. Heath, Janine Tomkins, Denise A. Figlewicz, Paul G. Ince, Pamela J. Shaw

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 405 KB

english, 2002

28

Co-ordinate transcriptional regulation of dopamine synthesis genes by α-synuclein in human neuroblastoma cell lines

Melisa J. Baptista, Casey O'Farrell, Sneha Daya, Rili Ahmad, David W. Miller, John Hardy, Matthew J. Farrer, Mark R. Cookson

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 224 KB

english, 2003

29

α-Synuclein and neuronal cell death

Journal:

Molecular Neurodegeneration

Year:

2009

Language:

english

File:

PDF, 641 KB

english, 2009

30

Three-dimensional reconstruction of human embryonic notochords: Clue to the pathogenesis of chordoma

Dr. Jonathan R. Salisbury, Mark H. Deverell, M. John Cookson, William F. Whimster

Journal:

The Journal of Pathology

Year:

1993

Language:

english

File:

PDF, 417 KB

english, 1993

31

Beyond instructional systems: A performance technology degree

Clare Ruckdeschel, Michael Yarter, Mary Ann Rivecdo, Ivan Cortes, Mark S. Cookson

Journal:

Performance Improvement

Year:

1998

File:

PDF, 1.03 MB

1998

32

Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1

Elisa Greggio, Patrick A. Lewis, Marcel P. Van Der Brug, Rili Ahmad, Alice Kaganovich, Jinhui Ding, Alexandra Beilina, Acacia K. Baker, Mark R. Cookson

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 1.18 MB

english, 2007

33

MKK6 binds and regulates expression of Parkinson’s disease-related protein LRRK2

Cindy H. Hsu, Diane Chan, Elisa Greggio, Shamol Saha, Maria D. Guillily, Andrew Ferree, Kesav Raghavan, Grace C. Shen, Lilach Segal, Hoon Ryu, Mark R. Cookson, Benjamin Wolozin

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 740 KB

english, 2010

34

Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant

Veronique Daniëls, Renée Vancraenenbroeck, Bernard M. H. Law, Elisa Greggio, Evy Lobbestael, Fangye Gao, Marc De Maeyer, Mark R. Cookson, Kirsten Harvey, Veerle Baekelandt, Jean-Marc Taymans

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 647 KB

english, 2011

35

Astrocytes in Parkinson’s disease and DJ-1

David N. Hauser, Mark R. Cookson

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 86 KB

english, 2011

36

Emerging pathways in genetic Parkinson's disease: Potential role of ceramide metabolism in Lewy body disease

Jose Bras, Andrew Singleton, Mark R. Cookson, John Hardy

Journal:

Year:

2008

Language:

english

File:

PDF, 323 KB

english, 2008

37

Parkin deficiency disrupts calcium homeostasis by modulating phospholipase C signalling

Anna Sandebring, Nodi Dehvari, Monica Perez-Manso, Kelly Jean Thomas, Elena Karpilovski, Mark R. Cookson, Richard F. Cowburn, Angel Cedazo-Mínguez

Journal:

Year:

2009

Language:

english

File:

PDF, 623 KB

english, 2009

38

Oxidative Stress and Motor Neurone Disease

Mark R. Cookson, Pamela J. Shaw

Journal:

Brain Pathology

Year:

1999

Language:

english

File:

PDF, 248 KB

english, 1999

39

Electron transfer reagent binding sites on plastocyanin

Cookson, David J., Hayes, Mark T., Wright, Peter E.

Journal:

Year:

1980

File:

PDF, 248 KB

1980

40

Neurons inflict self-harm

Cookson, Mark R

Journal:

Nature Medicine

Year:

2005

Language:

english

File:

PDF, 659 KB

english, 2005

41

The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease

Cookson, Mark R.

Journal:

Nature Reviews Neuroscience

Year:

2010

Language:

english

File:

PDF, 358 KB

english, 2010

42

Parkin’s substrates and the pathways leading to neuronal damage

Mark R. Cookson

Journal:

NeuroMolecular Medicine

Year:

2003

Language:

english

File:

PDF, 144 KB

english, 2003

43

Aging—RNA in development and disease

Mark R. Cookson

Journal:

Wiley Interdisciplinary Reviews: RNA

Year:

2012

Language:

english

File:

PDF, 246 KB

english, 2012

44

Integrating pathway analysis and genetics of gene expression for genome-wide association study of basal cell carcinoma

Mingfeng Zhang, Liming Liang, Nilesh Morar, Anna L. Dixon, G. Mark Lathrop, Jun Ding, Miriam F. Moffatt, William O. C. Cookson, Peter Kraft, Abrar A. Qureshi, Jiali Han

Journal:

Year:

2012

Language:

english

File:

PDF, 266 KB

english, 2012

45

Measurement and correction of parasitic sextupole components in magnetic quadrupole lenses

Mark B.H. Breese, David N. Jamieson, John A. Cookson

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1990

Language:

english

File:

PDF, 928 KB

english, 1990

46

A high brightness lithium metal ion source for nuclear microprobe applications

Mark B.H. Breese, J.A. Cookson, J.M. Cole, A.E. Ledbury

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1991

Language:

english

File:

PDF, 450 KB

english, 1991

47

The effect of parasitic sextupole fields on nuclear microprobe resolution

Mark Breese, J.A. Cookson

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1991

Language:

english

File:

PDF, 600 KB

english, 1991

48

Expression of PINK1 mRNA in human and rodent brain and in Parkinson's disease

Jeff G. Blackinton, Anna Anvret, Alexandra Beilina, Lars Olson, Mark R. Cookson, Dagmar Galter

Journal:

Year:

2007

Language:

english

File:

PDF, 1.19 MB

english, 2007

49

Deep sequencing of coding and non-coding RNA in the CNS

Marcel van der Brug, Michael A. Nalls, Mark R. Cookson

Journal:

Year:

2010

Language:

english

File:

PDF, 462 KB

english, 2010

50

Superoxide-induced nitric oxide release from cultured glial cells

Philip Manning, Mark R Cookson, Calum J McNeil, Denise Figlewicz, Pamela J Shaw

Journal:

Year:

2001

Language:

english

File:

PDF, 309 KB

english, 2001